The study of oncolytic viruses reproduction in organ cultures of human lymphoid tumors

Onkogematologiâ

A. V. Lipatova¹  D. V. Kochetkov¹  P. M. Chumakov¹  F. E. Babaeva²  S. K. Kravchenko² 

[1] Engelhardt Institute of Molecular Biology, Russian Academy of Sciences;National Research Center for Hematology, Ministry of Health of Russia;

关键词: oncolytic viruses;    lymphomas;    chemotherapy;    immunotherapy;    cell cultures;   

DOI  :  10.17650/1818-8346-2019-14-4-84-89

来源: DOAJ

【 摘 要 】

Oncolytic viruses are promising agents for the treatment of various types of tumors, including malignant non-Hodgkin lymphomas. In order to identify the most effective candidates from a wide panel of non-pathogenic antitumor strains, a study was carried out of their ability to reproduce in short-term cultures of lymphoid tumor cells. Also, tumor cell cultures were characterized in relation to the presence of specific viral receptors CD54, CD55, CD155 on their surface.

【 授权许可】

Unknown