期刊论文详细信息
Microorganisms
Staphylococcus epidermidis and Cutibacterium acnes: Two Major Sentinels of Skin Microbiota and the Influence of Cosmetics
Mathilde Fournière1  Gilles Bedoux1  Thomas Latire1  Djouhar Souak2  MarcG. J. Feuilloley2 
[1] Laboratoire de Biotechnologie et Chimie Marines LBCM EA 3884, IUEM, Université Bretagne Sud, 56000 Vannes, France;Laboratoire de Microbiologie Signaux et Microenvironment LMSM EA4312, Université de Rouen Normandie, 27000 Évreux, France;
关键词: skin microbiota;    biofilm;    cosmetic;    Staphylococcus epidermidis;    Cutibacterium acnes;   
DOI  :  10.3390/microorganisms8111752
来源: DOAJ
【 摘 要 】

Dermatological and cosmetics fields have recently started to focus on the human skin microbiome and microbiota, since the skin microbiota is involved in the health and dysbiosis of the skin ecosystem. Amongst the skin microorganisms, Staphylococcus epidermidis and Cutibacterium acnes, both commensal bacteria, appear as skin microbiota sentinels. These sentinels have a key role in the skin ecosystem since they protect and prevent microbiota disequilibrium by fighting pathogens and participate in skin homeostasis through the production of beneficial bacterial metabolites. These bacteria adapt to changing skin microenvironments and can shift to being opportunistic pathogens, forming biofilms, and thus are involved in common skin dysbiosis, such as acne or atopic dermatitis. The current evaluation methods for cosmetic active ingredient development are discussed targeting these two sentinels with their assets and limits. After identification of these objectives, research of the active cosmetic ingredients and products that maintain and promote these commensal metabolisms, or reduce their pathogenic forms, are now the new challenges of the skincare industry in correlation with the constant development of adapted evaluation methods.

【 授权许可】

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