Neglected aspects of tick-borne rickettsioses

Parasites & Vectors

Aránzazu Portillo¹  José Antonio Oteo¹  Markéta Nováková²  Laura Tomassone³  Rita de Sousa⁴ 

[1] Center of Rickettsiosis and Arthropod-Borne Diseases, Hospital San Pedro-CIBIR;Department of Biology, Faculty of Medicine, Masaryk University;Department of Veterinary Sciences, University of Turin;National Institute of Health Dr. Ricardo Jorge;

关键词: Rickettsia spp.;    Ticks;    Vertebrate hosts;    Candidatus;    Epidemiology;   

DOI  :  10.1186/s13071-018-2856-y

来源: DOAJ

【 摘 要 】

Abstract Rickettsioses are among the oldest known infectious diseases. In spite of this, and of the extensive research carried out, many aspects of the biology and epidemiology of tick-borne rickettsiae are far from being completely understood. Their association with arthropod vectors, the importance of vertebrates as reservoirs, the rarity of clinical signs in animals, or the interactions of pathogenic species with rickettsial endosymbionts and with the host intracellular environment, are only some examples. Moreover, new rickettsiae are continuously being discovered. In this review, we focus on the ‘neglected’ aspects of tick-borne rickettsioses and on the gaps in knowledge, which could help to explain why these infections are still emerging and re-emerging threats worldwide.

【 授权许可】

Unknown