A human beta cell line with drug inducible excision of immortalizing transgenes

Molecular Metabolism

Cécile Machado¹  Emilie Bricout-Neveu¹  Paul Czernichow¹  Marie-José Lecomte¹  Severine Pechberty¹  Maud Grenier-Godard¹  Raphaël Scharfmann²  Claire Colace³  Marion Benazra³  Philippe Ravassard³  Michele Solimena⁴  Andreas Müller⁴ 

[1] Endocells, Pépinière d'entreprises Institut du Cerveau et de la Moelle, 75007 Paris, France;INSERM, U1016, Institut Cochin, Faculté de Médecine, Université Paris Descartes, Sorbonne Paris Cité, 75014 Paris, France;Institut du cerveau et de la moelle (ICM), Biotechnology & Biotherapy Team, 75013 Paris, France;Paul Langerhans Institute of the Helmholtz Center Munich at the University Hospital and Faculty of Medicine, TU Dresden, 01307 Dresden, Germany;

关键词: Cell engineering;    Human pancreatic beta cell line;    Conditional immortalization;    Tamoxifen inducible CRE;    Human beta cell function;   

DOI  :  10.1016/j.molmet.2015.09.008

来源: DOAJ

【 授权许可】

Unknown