Outcomes of transitional care programs on adolescent chronic inflammatory systemic diseases: systematic review and meta-analyses

Pediatric Rheumatology Online Journal

Manuel Enrique de la O-Cavazos¹  Nadina Rubio-Pérez¹  Ana Victoria Villarreal-Treviño¹  Lesli Moreno-Hernandez¹  Fernando García-Rodríguez¹  Rodrigo García-Pérez¹  Joel Omar Jáquez-Quintana²  Karina Raygoza-Cortez³  Leticia Elizabeth Garza Lopez³  Ana Cecilia Arana-Guajardo⁴ 

[1] Department of Pediatrics, School of Medicine and University Hospital “Dr. José E. González”, Universidad Autónoma de Nuevo León;Gastroenterology Service and Department of Internal Medicine, School of Medicine and University Hospital “Dr. José E. González”, Universidad Autónoma de Nuevo León;Plataforma INVEST Medicina UANL-KER Unit Mayo Clinic (KER Unit Mexico), Universidad Autónoma de Nuevo León;Servicio de Reumatología, Instituto de Medicina Interna. Escuela Nacional de Medicina Sistema Tec Salud;

关键词: Transition program;    Chronic conditions;    Inflammatory bowel disease;    Juvenile idiopathic arthritis;    Systematic review;   

DOI  :  10.1186/s12969-022-00670-1

来源: DOAJ

【 摘 要 】

Abstract Background Patients with juvenile chronic inflammatory systemic diseases (jCID) are vulnerable to many circumstances when transitioning to adult-centered healthcare; this increases the burden of disease and worsen their quality of life. Methods MEDLINE, Embase, Web of Science and Scopus were searched from inception to March 16th, 2021. We included observational, randomized controlled trials and quasi-experimental studies that evaluated a transitional care program for adolescents and young adults with jCIDs. We extracted information regarding health-related quality of life, disease activity, drop-out rates, clinical attendance rates, hospital admission rates, disease-related knowledge, surgeries performed, drug toxicity and satisfaction rates. Results Fifteen studies met our inclusion criteria. The implementation of transition programs showed a reduction on hospital admission rates for those with transition program (OR 0.28; 95% CI 0.13 to 0.61; I 2 = 0%; p = 0.97), rates of surgeries performed (OR 0.26; 95% CI 0.12 to 0.59; I 2 = 0%; p = 0.50) and drop-out rates from the adult clinic (OR 0.23; 95% CI 0.12 to 0.46; I 2 = 0%; p = 0.88). No differences were found in other outcomes. Conclusion The available body of evidence supports the implementation of transition programs as it could be a determining factor to prevent hospital admission rates, surgeries needed and adult clinic attendance rates.

【 授权许可】

Unknown