Silico-tuberculosis and associated risk factors in central province of Iran

The Pan African Medical Journal

Mansooreh Jabbariasl¹  Aliasghar Farazi² 

[1] Department of Disease Control and Prevention, Health Center of Markazi Province, Arak University of Medical Sciences, Arak, Iran;Department of Infectious Diseases, School of Medicine, Arak University of Medical Sciences, Arak, Iran;

关键词: prevalence;    silicosis;    tuberculosis;   

DOI  :  10.11604/pamj.2015.20.333.4993

来源: DOAJ

【 摘 要 】

INTRODUCTION: co-existence of silicosis and tuberculosis is known as silico-tuberculosis. This article review the frequency of silicosis and tuberculosis in workers who exposed to silica and evaluate influencing factors that may increase the risk of silico-tuberculosis. METHODS: an analytical cross-sectional study was performed in silica exposed workers in central province of Iran during 2011-2012. Sampling method was un-randomized and considering all workers who at least 6 months exposed to silica. The study was done via questionnaire, clinical examination, spirometry, chest x-ray and tuberculosis investigations. RESULTS: a total of 3121 workers were included in the study, the mean age of participants was 43.1,12.4 years, and mean employment duration 14.9,6.8 years. Prevalence of TB in silica-exposed workers without silicosis was 172 cases per 100 000 people and prevalence in silicosis cases was 917 cases per 100 000 people. Incidence of TB in silica-exposed workers without silicosis was 69 cases per 100 000 people and incidence in silicosis cases was 459 cases per 100 000 people. The frequency of LTBI/TB was higher in age over thirty years old (P = 0.02), in workers with employment duration over 10 years (P = 0.004), in workers with exposure duration over 5 years (P = 0.03) and smokers with over 5 pack-years (P = 0.01).

【 授权许可】

Unknown