The prevalence and phenotypic manifestations of polycystic ovary syndrome (PCOS) among infertile Sudanese women: a cross-sectional study

BMC Women's Health

Abdel B. A. Ahmed¹  Bahaeldin Hassan¹  Manal E. Sharif¹  Abdalla Abusham¹  Ishag Adam²  Mohamed A. Ahmed³  Alawia N. Elasam³ 

[1] College of Medicine, King Khalid University;Department of Obstetrics and Gynecology, Unaizah College of Medicine and Medical Sciences, Qassim University;Faculty of Medicine, University of Khartoum;

关键词: Phenotype;    Polycystic ovary syndrome (PCOS);    Infertility;    Manifestations;   

DOI  :  10.1186/s12905-022-01762-6

来源: DOAJ

【 摘 要 】

Plain English summary Polycystic ovary syndrome (PCOS) is a global health problem associated with significant drawbacks during reproductive life. Few published studies have been conducted in Africa (including Sudan) addressing the clinical manifestations and phenotypic presentation of the disease. Therefore, we aimed to evaluate the clinical and biochemical presentation of the different PCOS phenotypes among infertile Sudanese women. A total of 368 infertile women with PCOS from a fertility center in Khartoum, Sudan, participated in the study. Clinical, hormonal, and ultrasonographic characteristics were described and compared between the four phenotype groups of PCOS. In this regard, Sudanese women uniquely expressed phenotype D as the most prevalent, and this does not match with the global distribution of PCOS phenotypes. Moreover, women with phenotype A were older and had high mean blood pressure, and a higher waist/hip ratio was observed among women with phenotype D. More epidemiological studies on this subject are needed in the region due to geographical, ethnic, and genetic variations.

【 授权许可】

Unknown