A Case of DRESS Syndrome Associated with Piperacillin-Tazobactam Treatment and Literature Review

Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi

Seven ULUDOKUMACI¹  Ali MERT¹  Mücahit YEMİŞEN¹ 

[1] Department of Infectious Diseases and Clinical Microbiology, Faculty of Cerrahpasa Medicine, University of Istanbul, Istanbul, Turkey;

关键词: DRESS syndrome;    Eosinophilia;    Fever;    Piperacillin-tazobactam;   

DOI  :  

来源: DOAJ

【 摘 要 】

A 47-year-old type-2 diabetic male patient was hospitalized with diabetic foot infection, and piperacillin-tazobactam treatment was initiated. In the 3rd week of treatment, fever, malaise, myalgia, leukopenia, eosinophilia, and elevations of transaminases and acute phase reactants developed. Cultures remained sterile, and symptoms regressed with a change of medication and steroid administration. The clinical situation was accepted as “drug rash with eosinophilia and systemic symptoms” (DRESS) syndrome, which is discussed in detail.

【 授权许可】

Unknown