Molecular Hydrogen: A Promising Adjunctive Strategy for the Treatment of the COVID-19

Frontiers in Medicine

Keliang Xie¹  Naqi Lian²  Yuzun Wang²  Zhen Wang²  Yingning Li²  Weiqiang Zheng² 

[1] College of Anesthesiology, Translational Research Institute of Intensive Care Medicine, College of Anesthesiology, Weifang Medical University, Weifang, China;Department of Anesthesiology, Tianjin Medical University General Hospital, Tianjin Research Institute of Anesthesiology, Tianjin, China;Department of Critical Care Medicine, Tianjin Medical University General Hospital, Tianjin, China;

关键词: COVID-19;    molecular hydrogen;    inflammation;    cytokines;    treatment;   

DOI  :  10.3389/fmed.2021.671215

来源: DOAJ

【 摘 要 】

Coronavirus disease 2019 (COVID-19) is an acute respiratory disease caused by a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which has no specific and effective treatment. The pathophysiological process of the COVID-19 is an excessive inflammatory response after an organism infects with a virus. Inflammatory storms play an important role in the development of the COVID-19. A large number of studies have confirmed that hydrogen has a therapeutic effect on many diseases via inhibiting excessive inflammatory cells and factors. Recently, a study led by the Academician Zhong Nanshan in China on the treatment of the patients with the COVID-19 by inhalation of a mixed gas composed of hydrogen and oxygen has attracted widespread international attention and hydrogen therapy has also been included in a new treatment plan for the COVID-19 in China. This study mainly describes the mechanism of occurrence of the COVID-19, summarizes the therapeutic effects and underlying mechanisms of hydrogen on the critical disease, and analyzes the feasibility and potential therapeutic targets of hydrogen for the treatment of the COVID-19.

【 授权许可】

Unknown