Effect of THz spectra of L-Arginine molecules by the combination of water molecules

iScience

Meilin Wu¹  Lei Hou¹  Wei Shi²  Haiqing Wang²  Chunhui Li²  Zhiquan Wang²  Chaofan Li² 

[1] Corresponding author;Key Laboratory of Ultrafast Photoelectric Technology and Terahertz Science in Shaanxi, Xi’an University of Technology, Xi’an 710048, China;

关键词: Physics;    Photonics;    Radiation physics;   

DOI  :  

来源: DOAJ

【 摘 要 】

Summary: Most biomolecules are biologically active only in water; hence, it is worth investigating whether THz spectra of biomolecules are affected by the combination of water molecules and biomolecules. In this report, by combining the sample cell with the THz-TDS system, the THz spectra of L-Arginine crystal as well as its hydrate and aqueous solution are measured. The experimental results show that L-Arginine crystal and its hydrate share the same three absorption peaks at 0.99, 1.46, and 1.7 THz, respectively. But the trend of characteristic absorption spectrum of L-arginine solution is almost identical to that of free water. Because the contents of free water and hydrated water are different in many diseased and normal tissues, the diseased tissues can be detected according to the difference in THz spectral information. The proposed approach provides a reliable means for the detection of pathological changes of active molecules and tissues.

【 授权许可】

Unknown