A Review on the Respiratory System Toxicity of Carbon Nanoparticles

International Journal of Environmental Research and Public Health

Ramzi Kafoury¹  Paul B. Tchounwou¹  Maricica Pacurari¹  Kristine Lowe² 

[1] Biology Department, College of Science, Engineering, and Technology, Jackson State University, Jackson, MS 39217, USA;Biology Department, The University of Texas Rio Grande Valley, Edinburg, TX 78539, USA;

关键词: CNF;    CNT;    respiratory pathology;    toxicological pathways;    exposure levels;   

DOI  :  10.3390/ijerph13030325

来源: DOAJ

【 摘 要 】

The respiratory system represents the main gateway for nanoparticles’ entry into the human body. Although there is a myriad of engineered nanoparticles, carbon nanoparticles/nanotubes (CNPs/CNTs) have received much attention mainly due to their light weight, very high surface area, durability, and their diverse applications. Since their discovery and manufacture over two decades ago, much has been learned about nanoparticles’ interactions with diverse biological system models. In particular, the respiratory system has been of great interest because various natural and man-made fibrous particles are known to be responsible for chronic and debilitating lung diseases. In this review, we present up-to-date the literature regarding the effects of CNTs or carbon nanofibers (CNFs) on the human respiratory system with respect to respiratory toxicity pathways and associated pathologies. This article is intended to emphasize the potentially dangerous effects to the human respiratory system if inadequate measures are used in the manufacture, handling, and preparation and applications of CNP or CNP-based products.

【 授权许可】

Unknown