Fractal Dimension and Texture Analysis in the Assessment of Experimental Laser-Induced Periodic Surface Structures (LIPSS) Dental Implant Surface—In Vitro Study Preliminary Report

Materials

Tomasz Gębarowski¹  Paweł Kubasiewicz-Ross²  Jakub Hadzik²  Marzena Dominiak²  Kamil Jurczyszyn²  Marcin Kozakiewicz³  Ewa Barg⁴  Aneta Cieśla-Niechwiadowicz⁴  Tomasz Gedrange⁵  Wojciech Simka⁶  Ernest Szajna⁷  Anna Trzcionka Szajna⁸ 

[1] Department of Biostructure and Animal Physiology, Wroclaw University of Environmental and Life Sciences, Kożuchowska 1/3, 51-631 Wroclaw, Poland;Department of Dental Surgery, Faculty of Medicine and Dentistry, Medical University of Wroclaw, ul. Krakowska 26, 50-425 Wroclaw, Poland;Department of Maxillofacial Surgery, Faculty of Military Medicine, Medical University of Lodz, 90-151 Łódź, Poland;Department of Medical Science Foundation, Faculty of Pharmacy, Wroclaw Medical University, Borowska 211, 50-556 Wroclaw, Poland;Department of Orthodontics, TU Dresden, 01062 Dresden, Germany;Faculty of Chemistry, Silesian University of Technology, 44-100 Gliwice, Poland;KMB Catalyst, 43-175 Wyry, Poland;NanoPrime, 39-200 Dębica, Poland;

关键词: implant topography;    fractal dimension analysis;    LIPSS;    laser surface;    texture analysis;   

DOI  :  10.3390/ma15082713

来源: DOAJ

【 摘 要 】

Laser-induced periodic surface structures (LIPSS) are the sub-wavelength periodic nanostructures generated by the femtosecond laser. Implant topography and its nanostructural changes can be important for biomedical applications. In order to compare the surface topography of different implants, appropriate mathematical and physical descriptive methods should be provided. The aim of the study was to evaluate the experimental LIPSS-based—Low Spatial Frequency LIPSS (LSFL) dental implant surfaces. Novel methods of surface analysis, such as Fractal Dimension Analysis and Texture Analysis, were compared to the standard surface roughness evaluation. Secondary, cell viability, and attachment tests were applied in order to evaluate the biological properties of the new titanium surface and to compare their correlation with the physical properties of the new surfaces. A Normal Human Dermal Fibroblast (NHDF) cytotoxicity test did not show an impact on the vitality of the cells. Our study has shown that the laser LIPSS implant surface modifications significantly improved the cell adhesion to the tested surfaces. We observed a strong correlation of adhesion and the growth of cells on the tested surface, with an increase in implant surface roughness with the best results for the moderately rough (2 μm) surfaces. Texture and fractal dimension analyses are promising methods to evaluate dental implants with complex geometry.

【 授权许可】

Unknown