Some aspects of the background symptomatic treatment of cognitive impairment of various severity types

Медицинский совет

I. S. Preobrazhenskaya¹ 

[1] First MSMU named after I.M.Sechenov;

关键词: деменция;    болезнь альцгеймера;    смешанная деменция;    деменция с тельцами леви;    умеренные когнитивные нарушения;    акатинол мемантин;    dementia;    alzheimer's disease;    mixed dementia;    dementia with lewy bodies;    mild cognitive impairment;    akatinol memantine;   

DOI  :  10.21518/2079-701X-2013-12-50-54

来源: DOAJ

【 摘 要 】

This literature review outlines the role of glutamatergic disturbances in the pathogenesis of cognitive disorders. There is data on the effectiveness of the glutamate NMDA-receptors antagonist - memantine - in patients with various dementias: Alzheimer's disease, dementia with Lewy bodies, vascular and mixed dementia. The authors share own positive experience with the drug Akatinol Memantine at various dementias. Options for administration of the drug in patients with mild cognitive impairment are discussed; results of a multicenter regional study are provided. The efficacy and safety of Akatinol Memantine as a medication to improve cognitive function is highlighted.

【 授权许可】

Unknown