BINOL as a chiral element in mechanically interlocked molecules

Beilstein Journal of Organic Chemistry

Matthias Krajnc¹  Jochen Niemeyer¹ 

[1] Faculty of Chemistry (Organic Chemistry) and Centre of Nanointegration Duisburg-Essen (CENIDE), University of Duisburg-Essen, Universitätsstr. 7, 45141 Essen, Germany;

关键词: axial chirality;    binol;    catenanes;    interlocked molecules;    rotaxanes;   

DOI  :  10.3762/bjoc.18.53

来源: DOAJ

【 摘 要 】

In this minireview we present the use of the axially chiral 1,1'-binaphthyl-2,2'-diol (BINOL) unit as a stereogenic element in mechanically interlocked molecules (MIMs). We describe the synthesis and properties of such BINOL-based chiral MIMs, together with their use in further diastereoselective modifications, their application in asymmetric catalysis, and their use in stereoselective chemosensing. Given the growing importance of mechanically interlocked molecules and the key advantages of the privileged chiral BINOL backbone, we believe that this research area will continue to grow and deliver many useful applications in the future.

【 授权许可】

Unknown