Mini-Review: Human Microbiome and Rheumatic Diseases

Frontiers in Cellular and Infection Microbiology

Işıl Üstün¹  Sibel Caglar¹  Meltem Vural¹  Benoit Gilbert²  Axel Finckh² 

[1] Physical Medicine and Rehabilitation Clinic, University of Health Sciences, Bakırkoy Dr. Sadi Konuk Training Hospital, Istanbul, Turkey;Rheumatology Division, Department of Medicine, Geneva University Hospital (HUG), Geneva, Switzerland;

关键词: microbiome;    rheumatic diseases;    etiopathogenesis;    spondylarthritis;    rheumatoid arthritis;   

DOI  :  10.3389/fcimb.2020.491160

来源: DOAJ

【 摘 要 】

Rheumatoid arthritis and spondyloarthropathy are the most common inflammatory rheumatic diseases. As the human microbiome is involved in the immune homeostasis, it has the potential to be a key factor in the development of autoimmune diseases and rheumatic diseases. In this article, we review the role of various human microbiota on the pathogenesis of rheumatic diseases, focusing on spondylarthritis and rheumatoid arthritis.

【 授权许可】

Unknown