Interobserver agreement in breast ultrasound categorization in the Mammography and Ultrasonography Study for Breast Cancer Screening Effectiveness (MUST-BE) trial: results of a preliminary study

Ultrasonography

Eun Jung Choi¹  You Me Kim²  Jin Hwa Lee³  Young Mi Park⁴  Young Joong Kim⁵  Keum Won Kim⁵  Eun Hye Lee⁶  Yun-Woo Chang⁷  Jae Kwan Jun⁸  Seri Hong⁸ 

[1] Department of Radiology and Research Institute of Clinical Medicine of Chonbuk National University-Biomedical Research Institute of Chonbuk National University Hospital, Chonbuk National University Medical School, Jeonju, Korea;Department of Radiology, Dankook University Hospital, Dankook University College of Medicine, Cheonan, Korea;Department of Radiology, Dong-A University Hospital, Dong-A University College of Medicine, Busan, Korea;Department of Radiology, Inje University Busan Paik Hospital, Busan, Korea;Department of Radiology, Konyang University Hospital, Konyang University College of Medicine, Daejeon, Korea;Department of Radiology, Soonchunhyang University Bucheon Hospital, Soonchunhyang University College of Medicine, Bucheon, Korea;Department of Radiology, Soonchunhyang University Seoul Hospital, Soonchunhyang University College of Medicine, Seoul, Korea;National Cancer Control Institute, National Cancer Center, Goyang, Korea;

关键词: Screening;    Neoplasms;    Breast neoplasms;    Ultrasonography;    Interobserver variability;   

DOI  :  10.14366/usg.18012

来源: DOAJ

【 摘 要 】

Purpose The purpose of this study was to record and evaluate interobserver agreement as quality control for the modified categorization of screening breast ultrasound developed by the Alliance for Breast Cancer Screening in Korea (ABCS-K) for the Mammography and Ultrasonography Study for Breast Cancer Screening Effectiveness (MUST-BE) trial. Methods Eight breast radiologists with 4-16 years of experience participated in 2 rounds of quality control testing for the MUST-BE trial. Two investigators randomly selected 125 and 100 cases of breast lesions with different ratios of malignant and benign lesions. Two versions of the modified categorization were tested. The initially modified classification was developed after the first quality control workshop, and the re-modified classification was developed after the second workshop. The re-modified categorization established by ABCS-K added size criteria and the anterior-posterior ratio compared with the initially modified classification. After a brief lecture on the modified categorization system prior to each quality control test, the eight radiologists independently categorized the lesions using the modified categorization. Interobserver agreement was measured using kappa statistics. Results The overall kappa values for the modified categorizations indicated moderate to substantial degrees of agreement (initially modified categorization and re-modified categorization: κ=0.52 and κ=0.63, respectively). The kappa values for the subcategories of category 4 were 0.37 (95% confidence interval [CI], 0.24 to 0.52) and 0.39 (95% CI, 0.31 to 0.49), respectively. The overall kappa values for both the initially modified categorization and the re-modified categorization indicated a substantial degree of agreement when dichotomizing the interpretation as benign or suspicious. Conclusion The preliminary results demonstrated acceptable interobserver agreement for the modified categorization.

【 授权许可】

Unknown