Acute Liver Failure after Treatment with Rivaroxaban for Aortic Thrombosis Associated with COVID-19 Infection and Methylenetetrahydrofolate Reductase Gene Polymorphism (C677T)

Case Reports in Gastroenterology

Milos Lalovac¹  Ivana Jukic²  Dorotea Bozic²  Zeljko Sundov²  Jonatan Vukovic²  Mirela Pavicic Ivelja³  Mislav Radic⁴ 

[1] Department of Gastroenterology and Hepatology, Merkur University Hospital, Zagreb, Croatia;Department of Gastroenterology and Hepatology, University Hospital of Split, Split, Croatia;Department of Infectious Diseases, University Hospital of Split, Split, Croatia;Division of Clinical Immunology and Rheumatology, Department of Internal Medicine, University Hospital of Split, Split, Croatia;

关键词: acute liver failure;    rivaroxaban;    covid-19;    arterial thrombosis;    thrombophilia;   

DOI  :  10.1159/000524791

来源: DOAJ

【 摘 要 】

Coronavirus disease-2019 (COVID-19) has become associated with prothrombotic state that could lead to severe arterial thrombotic complications. In the case of severe COVID-19 infection, hepatic dysfunction has been observed in more than 50% of patients. In this article, we present a case of aortic thrombosis associated with COVID-19 infection and methylenetetrahydrofolate reductase gene polymorphism (C677T) treated with rivaroxaban resulting in acute liver failure with fatal outcome.

【 授权许可】

Unknown