Liver transplantation for hepatocellular carcinoma

Современная онкология

M S Novruzbekov¹  I E Galankina¹  M Sh Khubutiya¹  O D Olisov¹  L N Zimina¹ 

[1] SFHI N.V.Sklifosovsky Research Institute for Emergency Care Moscow City Health Department;

关键词: liver transplantation;    hepatocellular carcinoma;    the milan criteria;    sorafenib;   

DOI  :  

来源: DOAJ

【 摘 要 】

Hepatocellular carcinoma (HCC) is one of the most frequent cancer, usually develops in cirrhotic liver. Liver transplantation (LT) is potentially curative treatment for HCC. A total of 50 patients with HCC underwent LT. Patients were divided and compared according to Milan criteria. Differences between pre - and post-operative assessment were evaluated. Overall survival (OS) and disease-free survival (DFS) were compared between groups. Patients within MC had a significant better 1-, 3- and 5-year survival than a control group: 100, 100, 87,5% vs. 58, 41 and 27% for DFS and 100, 100, 87,5% vs. 76,9, 45 and 29,5% for OS.Conclusion: long-term results in patients with HCC after LT is excellent if tumor characteristics are within the Milan criteria.

【 授权许可】

Unknown