Identifying Outcome Measures for Coronary Artery Disease Value-Based Contracting Using the Delphi Method

Cardiology and Therapy

Chester B. Good¹  Chronis Manolis¹  William H. Shrank¹  Elizabeth C. S. Swart¹  Natasha Parekh¹  Lynn M. Neilson¹  Rochelle Henderson² 

[1] Center for Value-Based Pharmacy Initiatives, UPMC Health Plan;Express Scripts Holding Company;

关键词: Antiplatelets;    Coronary artery disease (CAD);    Delphi method;    Drug costs;    Outcome measures;    Pharmaceuticals;   

DOI  :  10.1007/s40119-019-0132-7

来源: DOAJ

【 摘 要 】

Abstract Introduction Value-based contracts (VBCs) that link drug payments to disease-related performance metrics aim to increase the value and lower the cost of medications by aligning incentives and sharing risk between payers and pharmaceutical manufacturers. This study sought to identify outcome measures that are meaningful to key stakeholders to inform VBCs for coronary artery disease (CAD) medications. Methods We administered a modified Delphi survey to gather expert opinion from a diverse panel of patients (n = 9), cardiologists (n = 4), primary care physicians (n = 5), payers (n = 2), pharmacy benefits managers (n = 3), and pharmaceutical company representatives (n = 2). A list of 16 CAD-associated clinical indicators was generated from the literature and expert consultation. Delphi participants rated the importance of each outcome on a five-point Likert scale, and selected the three most meaningful outcomes. We defined consensus as ≥ 75% agreement on the importance of an outcome (Likert scores 4 or 5 or selection of an outcome as most meaningful). Results Eleven of 13 outcomes reached consensus for importance on the Likert scale. “Preventing heart attacks” was selected as the most meaningful outcome (80%) while “preventing death” ranked second (76%). Conclusions Our study results verify the utility of a widely used clinical CAD outcome measure, myocardial infarction events, for the purpose of pharmaceutical value-based contracting.

【 授权许可】

Unknown