Is visual inspection with acetic acid (VIA) a useful method of finding pre-invasive cervical cancer?

Clinical and Experimental Obstetrics & Gynecology

Robabeh Ghodssi-Ghasemabadi¹  Ghazaleh Fazli²  Mahdie Sanati³  Maliheh Arab⁴  Samaneh Saraeian⁵  Maryam Maktabi⁶  Atefeh Moridi⁷ 

[1] Department of Biostatistics, Tarbiat Modares University, 14117-13116 Tehran, Iran;Department of Developmental Biology, Science and Research University of Tehran, 1417466191 Tehran, Iran;Developmental biology, Science and Research University of Tehran, 1417466191 Tehran, Iran;Gynecology-Oncology, Cancer Research Center, Shahid Beheshti University of Medical Sciences, 1983963113 Tehran, Iran;Obstetrician & Gynecologist, Imam Hossein Medical Center, Shahid Beheshti University of Medical Sciences, 1983963113 Tehran, Iran;Obstetrics & Gynecology, Arak University of Medical Sciences, 38156879 Arak, Iran;Preventative Gynecology Research Center, Shahid Beheshti University of Medical Sciences, 1983963113 Tehran, Iran;

关键词: screening;    cervical cancer;    cervical dysplasia;    colposcopy;    visual inspection with acetic acid;    iran;   

DOI  :  10.31083/j.ceog.2021.01.2209

来源: DOAJ

【 摘 要 】

Purpose of investigation: The prospects for effective cytological screening in the majority of developing countries are limited. This study evaluated visual inspection with acetic acid (VIA) for the diagnosis of CIN 2-3 in case findings. Materials and Methods: In this prospective study, 1437 asymptomatic women were screened using VIA followed by colposcopy-biopsy of all cases. The predictive efficacy of VIA was determined based on pathological confirmation of CIN 2-3 on colposcopy-directed biopsy. Results: In 388 (27%) out of 1437 cases, the VIA was positive. In 31 (2.1%) cases, CIN 2-3 was confirmed on cervical biopsy. The sensitivity, specificity and negative predictive value (NPV) of the VIA were 41.9%, 73.3%, and 98.2%, respectively. Conclusion: The present study confirmed the value of VIA for screening, with sensitivity of 41.9% and NPV of 98.2%. Future studies should determine the best place for VIA testing alongside other types of testing in screening algorithms.

【 授权许可】

Unknown