Early diagnosis of spinal tuberculosis

Journal of the Formosan Medical Association

Chih-Wei Lee¹  Jui-Kuo Hung²  Yu-Min Chen³  Chang-Hua Chen⁴  Chun-Yuan Cheng⁵  Yu-Jun Chang⁶ 

[1] Department of Medical Imaging, Changhua Christian Hospital, Changhua City, Taiwan, ROC;Department of Orthopedic Surgery, Changhua Christian Hospital, Changhua City, Taiwan, ROC;Department of Pharmacy, Changhua Christian Hospital, Changhua City, Taiwan, ROC;Division of Infectious Diseases, Department of Internal Medicine, Changhua Christian Hospital, Changhua City, Taiwan, ROC;Division of Neurosurgery, Department of Surgery, Changhua Christian Hospital, Changhua City, Taiwan, ROC;Epidemiology and Biostatics Center, Changhua Christian Hospital, Changhua City, Taiwan, ROC;

关键词: algorithm;    decision-making;    early diagnosis;    review;    risk assessment;    spine;    tuberculosis;   

DOI  :  10.1016/j.jfma.2016.07.001

来源: DOAJ

【 摘 要 】

Spinal tuberculosis (STB) is a common manifestation of extrapulmonary tuberculosis (TB). STB accounts for around 2% of all cases of TB and around 15% of extrapulmonary TB cases. The World Health Organization has proposed a global strategy and targets for TB prevention, care, and control after 2015. Under this strategy, patients will receive standard care according to the recommendations and guidelines after confirmation of STB diagnosis. However, current recommendations and guidelines focus on disease and medication therapy management, and recommendations for early detection or decision-making algorithms regarding STB are lacking. In this review, we identified five key components for early diagnosis: (1) risk factors for STB; (2) common symptoms/signs of STB; (3) significant neuroradiological findings of STB; (4) significant laboratory findings of STB, including positive interferon-γ release assays and nonpyogenic evidence in initial laboratory data; and (5) significant clinical findings of STB. Individualized consideration for each patient with STB is essential, and we hope that the algorithm established in this review will provide a valuable tool for physicians who encounter cases of STB.

【 授权许可】

Unknown