An Electrochemical Way to Generate Amphiphiles from Hydrazones for the Synthesis of 1,2,4‐Triazole Scaffold Cyclic Compounds

ChemistryOpen

Dungai Wang¹  Xiao Liang¹  Heping Zhu¹  Prof. Dr. Yuanjiang Pan¹  Wangyu Li¹  Mingteng Xiong¹ 

[1]Department of Chemistry Zhejiang University Hangzhou 310027 China

关键词: amphiphiles;    cyclization;    electrooxidation;    one-pot reaction;    1,2,4-trizaole;   

DOI  :  10.1002/open.202100268

来源: DOAJ

【 摘 要 】

Abstract An electro‐oxidative cyclization pathway in which hydrazones are selected as starting materials to generate amphiphiles by reacting with benzylamines and benzamides was reported. This strategy successfully prepared a series of 1,2,4‐triazoles in satisfactory yields. Moreover, the use of cheap stainless steel as the anode, the feasibility to conduct the transformation as a one‐pot reaction and the proof that scaling‐up these reactions is possible make this transformation attractive for potential application in industry.

【 授权许可】

Unknown