Hypothalamic Integration of Metabolic, Endocrine, and Circadian Signals in Fish: Involvement in the Control of Food Intake

Frontiers in Neuroscience

María J. Delgado¹  José M. Cerdá-Reverter²  José L. Soengas³ 

[1] Departamento de Fisiología (Fisiología Animal II), Facultad de Biología, Universidad Complutense de MadridMadrid, Spain;Departamento de Fisiología de Peces y Biotecnología, Instituto de Acuicultura Torre de la Sal, Consejo Superior de Investigaciones CientíficasCastellón, Spain;Laboratorio de Fisioloxía Animal, Departamento de Bioloxía Funcional e Ciencias da Saúde, Facultade de Bioloxía, Universidade de VigoVigo, Spain;

关键词: food intake;    fish;    hypothalamus;    review;    nutrient sensing;    circadian rhythm;   

DOI  :  10.3389/fnins.2017.00354

来源: DOAJ

【 摘 要 】

The regulation of food intake in fish is a complex process carried out through several different mechanisms in the central nervous system (CNS) with hypothalamus being the main regulatory center. As in mammals, a complex hypothalamic circuit including two populations of neurons: one co-expressing neuropeptide Y (NPY) and Agouti-related peptide (AgRP) and the second one population co-expressing pro-opiomelanocortin (POMC) and cocaine- and amphetamine-regulated transcript (CART) is involved in the integration of information relating to food intake control. The production and release of these peptides control food intake, and the production results from the integration of information of different nature such as levels of nutrients and hormones as well as circadian signals. The present review summarizes the knowledge and recent findings about the presence and functioning of these mechanisms in fish and their differences vs. the known mammalian model.

【 授权许可】

Unknown