Association of Borderline Intellectual Functioning and Adverse Childhood Experience with adult psychiatric morbidity. Findings from a British birth cohort

BMC Psychiatry

Marco Bertelli¹  Eric Emerson²  Luis Salvador-Carulla³  Amaria Baghdadli⁴  Tuba Mutluer⁵  Fuad Ismayilov⁶  James Harris⁷  Angela Hassiotis⁸  Emma Brown⁸  Kerim Munir⁹  David Helm⁹  Rafael Martínez-Leal^1,10  Jannelien Wieland^1,11  Ramon Novell-Alsina^1,12  Jordi Cid^1,12  Laura Vergés^1,12 

[1] CREA, Research and Clinical Centre, San Sebastiano Foundation;Centre for Disability Research & Policy, Faculty of Health Sciences, University of Sydney;Centre for Mental Health Research, Australian National University;Child and Adolescent Psychiatry Department, Montpellier Hospital University;Department of Child and Adolescent Psychiatry, Koc University Hospital;Department of Psychiatry, Azerbaijan Medical University;Developmental Neuropsychiatry, Department of Psychiatry and Behavioral Sciences, Bloomberg Children’s Center, The Johns Hopkins Hospital;Division of Psychiatry, University College London;Institute for Community Inclusion, Division of Developmental Medicine, Boston Children’s Hospital;Intellectual Disability and Developmental Disorders Research Unit (UNIVIDD), Fundació Villablanca, IISPV, Universitat Rovira i Virgili;Kristal Centre for Psychiatry and Intellectual Disability;Mental Health and Intellectual Disability Specialized Service, Catalan Health Govenment. Martí i Julià Hospital;

关键词: Borderline;    Intellectual;    Adversity;    Mental wellbeing;    Childhood;   

DOI  :  10.1186/s12888-019-2376-0

来源: DOAJ

【 摘 要 】

Abstract Background To examine whether Borderline Intellectual Functioning (BIF) and Adverse Childhood Experiences independently predict adult psychiatric morbidity. Methods We performed a secondary analysis of longitudinal data derived from the 1970 British Birth Cohort Study to examine whether BIF and Adverse Childhood Experiences independently predict adult mental distress as measured by the Malaise Inventory. Factor analysis was used to derive a proxy measure of IQ from cognitive testing at age 10 or 5. Variables that could be indicators of exposure to Adverse Childhood Experiences were identified and grouped into health related and socio-economic related adversity. Results Children with BIF were significantly more likely than their peers to have been exposed to Adverse Childhood Experiences (BIF mean 5.90, non-BIF mean 3.19; Mann-Whitney z = 31.74, p < 0.001). As adults, participants with BIF were significantly more likely to score above the cut-off on the Malaise Inventory. We found statistically significant relationships between the number of socio-economic Adverse Childhood Experiences and poorer adult psychiatric morbidity (r range 0.104–0.141, all p < 001). At all ages the indirect mediating effects of Adverse Childhood Experiences were significantly related to adult psychiatric morbidity. Conclusions The relationship between BIF and adult psychiatric morbidity appears to be partially mediated by exposure to Adverse Childhood Experiences. Where possible, targeting Adverse Childhood Experiences through early detection, prevention and interventions may improve psychiatric morbidity in this population group.

【 授权许可】

Unknown