Improved Corrosion Behavior and Biocompatibility of Porous Titanium Samples Coated with Bioactive Chitosan-Based Nanocomposites

Materials

Cristina García-Cabezón¹  Fernando Martín-Pedrosa¹  Yadir Torres²  Vanda Godinho²  Coral Salvo-Comino³ 

[1] Departamento de Ciencia de Materiales e Ingeniería Metalúrgica, Escuela de Ingenierías Industriales, Universidad de Valladolid, Calle Paseo del Cace 59, 47011 Valladolid, Spain;Departamento de Ingeniería y Ciencia de los Materiales y del Transporte, Escuela Politécnica Superior, Calle Virgen de África 7, 41011 Sevilla, Spain;Departamento de Química Inorgánica, Escuela de Ingenierías Industriales, Universidad de Valladolid, Calle Paseo del Cace 59, 47011 Valladolid, Spain;

关键词: porous titanium implants;    electrodeposition;    Chitosan/AgNPs;    Chitosan/Hydroxyapatite coatings;    corrosion characterization;    in vitro behavior;   

DOI  :  10.3390/ma14216322

来源: DOAJ

【 摘 要 】

Porous titanium implants can be a good solution to solve the stress shielding phenomenon. However, the presence of pores compromises mechanical and corrosion resistance. In this work, porous titanium samples obtained using a space-holder technique are coated with Chitosan, Chitosan/AgNPs and Chitosan/Hydroxyapatite using only one step and an economic electrodeposition method. The coatings’ topography, homogeneity and chemical composition were analyzed. A study of the effect of the porosity and type of coating on corrosion resistance and cellular behavior was carried out. The electrochemical studies reveal that porous samples show high current densities and an unstable oxide film; therefore, there is a need for surface treatments to improve corrosion resistance. The Chitosan coatings provide a significant improvement in the corrosion resistance, but the Chitosan/AgNPs and Chitosan/HA coatings showed the highest protection efficiency, especially for the more porous samples. Furthermore, these coatings have better adherence than the chitosan coatings, and the higher surface roughness obtained favors cell adhesion and proliferation. Finally, a combination of coating and porous substrate material with the best biomechanical balance and biofunctional behavior is proposed as a potential candidate for the replacement of small, damaged bone tissues.

【 授权许可】

Unknown