Probe-based confocal laser endomicroscopy in diagnosis of desquamative interstitial pneumonia in nonsmoker

Monaldi Archives for Chest Disease

Igor V. Vasilev¹  Alexey D. Ushkov²  Tatiana A. Novickaya²  Irina A. Tabanakova²  Vera V. Sysoeva²  Piotr K. Yablonskii³  Igor S. Mamenko³  Sultan M. Gasanmagomedov⁴ 

[1] St. Petersbug State University;St. Petersburg Scientific Research Institute of Phthisiopulmonology, Ministry of Health of Russia, St. Petersburg;St. Petersburg Scientific Research Institute of Phthisiopulmonology;St. PetersburgResearch Institute of Phthisiopulmonology, Ministry of Health of Russia, St. Petersburg;

关键词: confocal laser endomicroscopy;    optical biopsy;    interstitial lung diseases;    idiopathic interstitial pneumonias;    desquamative interstitial pneumonia;   

DOI  :  10.4081/monaldi.2019.1052

来源: DOAJ

【 摘 要 】

Desquamative interstitial pneumonia is a rare disease that is predominantly associated with smoking. Surgical biopsy is usually recommended for the diagnosis of this disorder. Probe-based confocal laser endomicroscopy (pCLE) is a new method of minimally invasive in vivo microscopic image of airways and alveoli. We use this method for desquamative interstitial pneumonia in nonsmoker. The pCLE image shows thickened intra-alveolar septae and clusters of autofluorescent cells within the alveoli, which is unusual for non-smoking patients. We think this pattern can be used for differential diagnosis of desquamative interstitial pneumonia in nonsmokers.

【 授权许可】

Unknown