Frontiers in Neurology | |
TAB-TICI Score: Successful Recanalization Score After Endovascular Thrombectomy in Acute Stroke | |
Hyo Suk Nam1  Woo-Keun Seo2  Byung Moon Kim3  Pyoung Jeon3  Young Dae Kim3  Jong-Won Chung4  Keon-Ha Kim4  Ji Hoe Heo5  Oh Young Bang5  Gyeung-Moon Kim6  | |
[1] Technology (SAIHST), Sungkyunkwan University, Seoul, South Korea;;Department of Digital Health, Samsung Advanced Institute for Health Science &Department of Neurology and Stroke Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea;Department of Neurology, Yonsei University College of Medicine, Seoul, South Korea;Department of Radiology, Samsung Medical Center, School of Medicine, Sungkyunkwan University, Seoul, South Korea;Interventional Neuroradiology, Yonsei University College of Medicine, Seoul, South Korea; | |
关键词: endovascular thrombectomy; outcome; performance; stroke; recanalization; | |
DOI : 10.3389/fneur.2021.692490 | |
来源: DOAJ |
【 摘 要 】
Background and Purpose: Successful reperfusion therapy is supposed to be comprehensive and validated beyond the grade of recanalization. This study aimed to develop a novel scoring system for defining the successful recanalization after endovascular thrombectomy.Methods: We analyzed the data of consecutive acute stroke patients who were eligible to undergo reperfusion therapy within 24 h of onset and who underwent mechanical thrombectomy using a nationwide multicenter stroke registry. A new score was produced using the predictors which were directly linked to the procedure to evaluate the performance of the thrombectomy procedure.Results: In total, 446 patients in the training population and 222 patients in the validation population were analyzed. From the potential components of the score, four items were selected: Emergency Room-to-puncture time (T), adjuvant devices used (A), procedural intracranial bleeding (B), and post-thrombectomy reperfusion status [Thrombolysis in Cerebral Infarction (TICI)]. Using these items, the TAB-TICI score was developed, which showed good performance in terms of discriminating early neurological aggravation [AUC 0.73, 95% confidence interval (CI) 0.67–0.78, P < 0.01] and favorable outcomes (AUC 0.69, 95% CI 0.64–0.75, P < 0.01) in the training population. The stability of the TAB-TICI score was confirmed by external validation and sensitivity analyses. The TAB-TICI score and its derived grade of successful recanalization were significantly associated with the volume of thrombectomy cases at each site and in each admission year.Conclusion: The TAB-TICI score is a valid and easy-to-use tool to more comprehensively define successful recanalization after endovascular thrombectomy in acute stroke patients with large vessel occlusion.
【 授权许可】
Unknown