TAB-TICI Score: Successful Recanalization Score After Endovascular Thrombectomy in Acute Stroke

Frontiers in Neurology

Hyo Suk Nam¹  Woo-Keun Seo²  Byung Moon Kim³  Pyoung Jeon³  Young Dae Kim³  Jong-Won Chung⁴  Keon-Ha Kim⁴  Ji Hoe Heo⁵  Oh Young Bang⁵  Gyeung-Moon Kim⁶ 

[1] Technology (SAIHST), Sungkyunkwan University, Seoul, South Korea;;Department of Digital Health, Samsung Advanced Institute for Health Science &Department of Neurology and Stroke Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea;Department of Neurology, Yonsei University College of Medicine, Seoul, South Korea;Department of Radiology, Samsung Medical Center, School of Medicine, Sungkyunkwan University, Seoul, South Korea;Interventional Neuroradiology, Yonsei University College of Medicine, Seoul, South Korea;

关键词: endovascular thrombectomy;    outcome;    performance;    stroke;    recanalization;   

DOI  :  10.3389/fneur.2021.692490

来源: DOAJ

【 摘 要 】

Background and Purpose: Successful reperfusion therapy is supposed to be comprehensive and validated beyond the grade of recanalization. This study aimed to develop a novel scoring system for defining the successful recanalization after endovascular thrombectomy.Methods: We analyzed the data of consecutive acute stroke patients who were eligible to undergo reperfusion therapy within 24 h of onset and who underwent mechanical thrombectomy using a nationwide multicenter stroke registry. A new score was produced using the predictors which were directly linked to the procedure to evaluate the performance of the thrombectomy procedure.Results: In total, 446 patients in the training population and 222 patients in the validation population were analyzed. From the potential components of the score, four items were selected: Emergency Room-to-puncture time (T), adjuvant devices used (A), procedural intracranial bleeding (B), and post-thrombectomy reperfusion status [Thrombolysis in Cerebral Infarction (TICI)]. Using these items, the TAB-TICI score was developed, which showed good performance in terms of discriminating early neurological aggravation [AUC 0.73, 95% confidence interval (CI) 0.67–0.78, P < 0.01] and favorable outcomes (AUC 0.69, 95% CI 0.64–0.75, P < 0.01) in the training population. The stability of the TAB-TICI score was confirmed by external validation and sensitivity analyses. The TAB-TICI score and its derived grade of successful recanalization were significantly associated with the volume of thrombectomy cases at each site and in each admission year.Conclusion: The TAB-TICI score is a valid and easy-to-use tool to more comprehensively define successful recanalization after endovascular thrombectomy in acute stroke patients with large vessel occlusion.

【 授权许可】

Unknown