Obesity Does Not Influence Delayed Gastric Emptying Following Pancreatoduodenectomy

Biology

Jörg C. Kalff¹  Christiane Pillny¹  Jana Enderes¹  Hanno Matthaei¹  Steffen Manekeller¹  Tim R. Glowka¹ 

[1] Department of Surgery, University Hospital Bonn, 53127 Bonn, Germany;

关键词: pancreaticoduodenectomy;    whipple;    obesity;    body mass index;    delayed gastric emptying;   

DOI  :  10.3390/biology11050763

来源: DOAJ

【 摘 要 】

Background: The data about obesity on postoperative outcome after pancreatoduodenectomy (PD) are inconsistent, specifically in relation to gastric motility and delayed gastric emptying (DGE). Methods: Two hundred and eleven patients were included in the study and patients were retrospectively analyzed in respect to pre-existing obesity (obese patients having a body mass index (BMI) ≥ 30 kg/m² vs. non-obese patients having a BMI < 30 kg/m², n = 34, 16% vs. n = 177, 84%) in relation to demographic factors, comorbidities, intraoperative characteristics, mortality and postoperative complications with special emphasis on DGE. Results: Obese patients were more likely to develop clinically relevant pancreatic fistula grade B/C (p = 0.008) and intraabdominal abscess formations (p = 0.017). However, clinically relevant DGE grade B/C did not differ (p = 0.231) and, specifically, first day of solid food intake (p = 0.195), duration of intraoperative administered nasogastric tube (NGT) (p = 0.708), rate of re-insertion of NGT (0.123), total length of NGT (p = 0.471) or the need for parenteral nutrition (p = 0.815) were equally distributed. Moreover, mortality (p = 1.000) did not differ between the two groups. Conclusions: Obese patients do not show a higher mortality rate and are not at higher risk to develop DGE. We thus show that in our study, PD is feasible in the obese patient in regard to postoperative outcome with special emphasis on DGE.

【 授权许可】

Unknown