Natural Products, Traditional Uses and Pharmacological Activities of the Genus Biebersteinia (Biebersteiniaceae)

Plants

Xiaona Jin¹  Xiaofeng Zhang¹  Lam-Son Phan Tran²  Benyin Zhang³  Hengxia Yin³  Dejun Zhang³  Huakun Zhou⁴ 

[1] Institute of Life Science Application, College of Medicine, Xi’an International University, Xi’an 710017, China;Institute of Research and Development, Duy Tan University, 03 Quang Trung, Da Nang 550000, Vietnam;State Key Laboratory of Plateau Ecology and Agriculture, Qinghai University, Xining 810016, China;The Key Laboratory of Restoration Ecology in Cold Region of Qinghai Province, Northwest Institute of Plateau Biology, Chinese Academy of Science, Xining 810008, China;

关键词: Biebersteinia;    Biebersteiniaceae;    chemical properties;    natural products;    traditional uses;    pharmacological activities;   

DOI  :  10.3390/plants9050595

来源: DOAJ

【 摘 要 】

Medicinal plants have been known as a rich source of natural products (NPs). Due to their diverse chemical structures and remarkable pharmacological activities, NPs are regarded as important repertoires for drug discovery and development. Biebersteinia plant species belong to the Biebersteiniaceae family, and have been used in folk medicines in China and Iran for ages. However, the chemical properties, bioactivities and modes of action of the NPs produced by medicinal Biebersteinia species are poorly understood despite the fact that there are only four known Biebersteinia species worldwide. Here, we reviewed the chemical classifications and diversity of the various NPs found in the four known Biebersteinia species. We found that the major chemical categories in these plants include flavonoids, alkaloids, phenylpropanoids, terpenoids, essential oils and fatty acids. We also discussed the anti-inflammatory, analgesic, antibacterial, antioxidant, antihypertensive and hypoglycemic effects of the four Biebersteinia species. We believe that the present review will facilitate the exploration of traditional uses and pharmacological properties of Biebersteinia species, extraction of the NPs and elucidation of their molecular mechanisms, as well as the development of novel drugs based on the reported properties and mode-of-action.

【 授权许可】

Unknown