MODIFICATION OF MYOCARDIUM FUNCTION AND PERFUSION AFTER LIVER TRANSPLANTATION. RESULTS OF MYOCARDIAL SCINTIGRAPHY

Vestnik Transplantologii i Iskusstvennyh Organov

E.D. Kotina¹  Y.O. Malinovskaya²  E.N. Ostroumov²  Y.G. Moysyuk³ 

[1] St. Petersburg State University, St. Petersburg, Russian Federation;V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Moscow, RussianFederation;V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Moscow, Russian FederationDepartment of Transplantology and Artificial Organs I.M. Sechenov First Moscow State Medical University, Moscow, Russian Federation;

关键词: liver transplantation, cirrhotic cardiomyopathy, ecg-gated single photon emission computed tomography (spect), myocardial perfusion imaging;   

DOI  :  10.15825/1995-1191-2014-2-52-59

来源: DOAJ

【 摘 要 】

Aim evaluated function and perfusion of myocardium in 12 cirrhotic patients before and after liver transplantation (LT).Materials and methods. ECG-gated single photon emission computed tomography (SPECT) was used.Results. It was found that hyperdynamics diminished liver transplantation: left ventricle (LV) end-systolic volume (ESV) rose from 23 to 33 ml (p = 0,026), LV ejection fraction decreased staying normal from 76 до 60% (p = 0,08), calculated cardiac output declined from 4941 to 3066 ml/min (p = 0,009), peak ejection rate (PER) from 314 to 218 ml/sec, (p = 0,003), peak fi lling rate decreased from 248 to 182 ml/sec (p = 0,037), eccentricity coeffi cient also decreased from 0,81 to 0,77 (p = 0,028). Local alteration of perfusion was found only in 2 cases.Conclusion. Hyperdynamic systolic dysfunction and diastolic dysfunction improve after liver transplantation. Further studies are required to estimate the applicability of SPECT in liver transplantation candidates’ evaluation.

【 授权许可】

Unknown