Fabrication of a nano-biocatalyst for regioselective acylation of arbutin

Green Chemistry Letters and Reviews

Yuxin Zhang¹  Xiaona Xie¹  Xiuyun Cui¹  Hong Zhuang¹  Lei Wang¹  Lu Zheng¹  He Huang¹  Zhi Wang¹ 

[1] Jilin University;

关键词: Enzyme immobilization;    nano-biocatalyst;    hybrid nanoparticle;    regioselective transesterification;    arbutin;   

DOI  :  10.1080/17518253.2018.1437226

来源: DOAJ

【 摘 要 】

A nano-biocatalyst has been successfully prepared via coordination between zinc ion and the nitrogen atoms of the amide groups in the Candida sp. 99-125 lipase. The as-prepared nanoparticle has an excellent hierarchical structure with a large number of separate petals. In regioselective acylation of arbutin, the nano-biocatalyst showed enhanced enzyme activities to about 4.3-folds than the free enzyme. Meanwhile, the prepared nano-biocatalyst exhibited good operational reusability and only about 6% of enzyme activity has lost during 10 continuous reaction-recycles.

【 授权许可】

Unknown