Development of noninvasive procedure for monitoring blood glucose level using gingival crevicular bleeding

Stomatološki glasnik Srbije

关键词: type 2 diabetes;    chronic periodontitis;    gingival crevicular fluid;    noninvasive method;    probing;   

DOI  :  10.2298/SGS1303124G

来源: DOAJ

【 摘 要 】

Introduction. Diabetes mellitus (DM) and chronic periodontitis are commonchronic diseases in adults. It is usually necessary to provide a sample ofcapillary blood to measure blood glucose level in diabetics. However, it ispossible to obtain blood during periodontal probing without any discomfort.The aim of the study was to evaluate accessibility of chair side noninvasivescreening method for blood glucose level in DM during routine periodontalexamination. Material and Methods. 15 non diabetics and 15 newly onset type 2diabetic patients with moderate to severe periodontitis were selected for thestudy after meeting inclusion and exclusion criteria. Periodontal pocketprobing was performed using Williams Graduated periodontal probe. Bloodoozing from gingival sulcus of anterior teeth following periodontal pocketprobing was collected with a stick of glucose self monitoring device. Ascontrol, finger stick capillary blood was taken. Results. Statisticallysignificant correlation was observed between the blood glucose level ingingival crevicular blood (GCB) and peripheral fasting blood (PFB) indiabetic subjects. The mean GCB glucose level in diabetic subjects was172.27±5.02 mg/dL while mean PFB glucose level was 167.80±8.87 mg/dL. Thecorrelation coefficients for diabetic and non diabetic subjects were r=0.715and r=0.619, respectively. Conclusion The results suggested that blood oozingduring routine periodontal examination may be used for DM screening in dentaloffice without the need for any extra procedure.

【 授权许可】

Unknown