Therapeutic Potential of Traditional Chinese Medicine on Inflammatory Diseases

Journal of Traditional and Complementary Medicine

Chih-Ching Yang¹  Chiang-Ting Chien²  Ping-Chia Li³  Wen-Hsin Tsai⁴  Wang-Chuan Chen⁵ 

[1] Bureau of Planning, Department of Health, Executive Yuan, Taipei, Taiwan.;Department of Life Science, National Taiwan Normal University, Taipei, Taiwan.;Department of Occupational Therapy, I-Shou University, Kaohsiung, Taiwan.;Department of Traditional Chinese Medicine, Taipei City Hospital Linsen (Chinese Medicine) Branch, Taipei, Taiwan.;The School of Chinese Medicine for Post Baccalaureate, I-Shou University, Kaohsiung, Taiwan.;

关键词: Apoptosis;    Autophagy;    Endoplasmic reticulum stress;    Inflammation;    Oxidative stress;    Traditional Chinese Medicine;   

DOI  :  10.4103/2225-4110.114898

来源: DOAJ

【 摘 要 】

Increased oxidative stress induces inflammation to several tissues/organs leading to cell death and long-term injury. Traditional Chinese Medicine (TCM) with antioxidant, anti-inflammatory, anti-apoptotic, and autophagic regulatory functions has been widely used as preventive or therapeutic strategy in modern medicine. Oxidative stress and inflammation have been widely reported to contribute to cigarette smoke–induced lung inflammation, hepatotoxicity, or sympathetic activation–induced liver inflammation, lipopolysaccharide-induced renal inflammation, and substance P–mediated neurogenic hyperactive bladder based on clinical findings. In this review, we introduce several evidences for TCM treatment including Monascus adlay (MA) produced by inoculating adlay (Cois lachrymal-jobi L. var. ma-yuen Stapf) with Monascus purpureus on lung injury, Amla (Emblica officinalis Gaertn. of Euphorbiaceae family) on hepatotoxin-induced liver inflammation, Virgate Wormwood Decoction (茵陳蒿湯 Yīn Chén Hāo tāng) and its active component genipin on sympathetic activation–induced liver inflammation, and green tea extract and its active components, catechins, or a modified TCM formula Five Stranguries Powder (五淋散 Wǔ Lín Sǎn) plus Crataegi Fructus (山楂 Shān Zhā) on hyperactive bladder. The pathophysiologic and molecular mechanisms of TCM on ameliorating inflammatory diseases are discussed in the review.

【 授权许可】

Unknown