A mathematical model for exchanging waves between cellular DNA and drug molecules and their roles in curing cancer

Results in Physics

M.R. Alharthi¹  Saad J. Almalki²  Mohamed S. Mohamed³  S.K. Elagan³  Mohamed F. El-Badawy³ 

[1] Corresponding author.;Department of Mathematics and Computer Science, Faculty of Science, Menoufiya University, Shebin Elkom, Egypt;Department of Mathematics and Statistics, College of Science, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia;

关键词: DNA;    Drugs;    Nivolumab;    Ipilimumab;    Survival;    Charged particles;   

DOI  :  

来源: DOAJ

【 摘 要 】

DNA could emit some waves and absorb or repel drugs. Thus, DNA waves have the main role in drug’s effects on cells. Recently, some scientists have shown that the probability for survival in patients who taken nivolumab plus ipilimumab is more than in patients who obtained ipilimumab alone. We show that the reason for these events is that some drug molecules which have more charges could be absorbed more by charges on DNA within cells. We propose a physical model for calculating the attractive forces between drugs and DNA within cells. In this model, a drug is formed from charged particles and by its motions along blood vessels, some electrical currents are emerged. From other side, DNA within cells are also formed from charged particles. Charges of DNA within cells interact with charges of drugs and consequently; DNA within cells vibrate. Consequently, a cellular current is emerged which interacts with drug currents and two electrical and magnetical forces are emerged. We show that by increasing number of charged atoms within drugs and DNA, the attractive forces between cells and drugs increase. Thus, a system which is formed from two drugs like nivolumab plus ipilimumab includes more charges respect to one drug like ipilimumab alone. Consequently, this combination is more absorbed by charges on DNA within cells and is more effective. This could be generalized to any other drug that can be used in curing cancers.

【 授权许可】

Unknown