Modern Technologies in the Examination of Patients with Optic Nerve Atrophy Due to Multiple Sclerosis

Oftalʹmologiâ

E. E. Ioyleva¹  M. S. Krivosheeva¹  E. Yu. Markova¹ 

[1] The S. Fyodorov Eye Microsurgery Federal State Institution;

关键词: multiple sclerosis;    optic nerve atrophy;    optic neuritis;    microperimetry;   

DOI  :  10.18008/1816-5095-2018-2S-246-253

来源: DOAJ

【 摘 要 】

Purpose: to develop an algorithm for testing patients with optic nerve atrophy due to MS using microperimetry with the different functional disorders.Patients and Methods. There were 20 patients (40 eyes) with the correct diagnosis of MS at the age of 33 ± 1.88 years in the study. The BCVA was from 0.1 to 1.0. Microperimetry was done on MP-1 (Nidek technologies, Vigonza, Italy) with the definition of mean sensitivity, stability and type of fixation. We chose the parameters of microperimetry: the research program, the size of the stimulus, the fixation mark and the test mode.Results. The best program for diagnosing central visual field defects was the program macula 12° 10 dB, for paracentral visual field defects – retina 40° 20 dB. The testing was conducted by using a standard stimulus Goldmann III, mark and survey mode is selected individually, according at the various types of functional disorders. The visual acuity was from 0.1 to 0.4 in 11 eyes with optic nerve atrophy. There were revealed absolute or relative defects of the central field of vision and the decreasing of mean sensitivity to 8.21 ± 2.3 dB, unstable central fixation — 71.18 ± 10, 3%. In 29 eyes with optic nerve atrophy and visual acuity 0.5–1.0 have been identified relative small central visual field defects and paracentral visual field defects in the inferior side with a decrease in sensitivity to 15,32 ± 0,84 dB in the area of 6° from the fixing point, stable central fixation 88,96 ± 2,9%.Conclusion. The authors developed an algorithm for testing patients with optic nerve atrophy due to MS. Using the algorithm identified the central and paracentral visual field defects with the decrease in the mean sensitivity.

【 授权许可】

Unknown