Marked prolongation of QRS duration after initiation of dronedarone therapy

Heart International

Conrad Genz¹  Ruediger C. Braun-Dullaeus¹  Alexander Schmeisser¹  Samir M. Said¹  Hans D. Esperer¹ 

[1]Section of Electrophysiology, Division of Cardiology, Otto-von-Guericke University, University Hospital Magdeburg, Magdeburg - Germany

关键词: Adverse drug events;    Antiarrhythmic drugs;    Atrial fibrillation;    Dronedarone;   

DOI  :  10.5301/HEART.2014.12491

来源: DOAJ

【 摘 要 】

Dronedarone is a relatively new antiarrhythmic drug and is held to be less proarrhythmic than comparable compounds, although its proarrhythmia potential in humans has not been sufficiently evaluated. We describe a so far unreported dronedarone effect, namely a significant alteration of both the morphology and the duration of the QRS complex on the electro cardiogram in a 41-year old patient with symptomatic paroxysmal atrial fibrillation.

【 授权许可】

Unknown