Detection and Characterization of Bat Sarbecovirus Phylogenetically Related to SARS-CoV-2, Japan

Emerging Infectious Diseases

关键词: betacoronavirus;    bat sarbecovirus;    Rhinolophus cornutus;    respiratory infections;    severe acute respiratory syndrome coronavirus 2;    SARS-CoV-2;   

DOI  :  10.3201/eid2612.203386

来源: DOAJ

【 摘 要 】

Epidemiology of bat Betacoronavirus, subgenus Sarbecovirus is largely unknown, especially outside China. We detected a sarbecovirus phylogenetically related to severe acute respiratory syndrome coronavirus 2 from Rhinolophus cornutus bats in Japan. The sarbecovirus’ spike protein specifically recognizes angiotensin-converting enzyme 2 of R. cornutus, but not humans, as an entry receptor.

【 授权许可】

Unknown