Risk factors for liver fibrosis progression in patients with chronic hepatitis C

Annals of Hepatology

Thierry Poynard¹  Mercedes de Torres¹ 

[1] Service d’Hépato-Gastroentérologie Groupe Hospitalier Pitié-Salpétriére;

关键词: Chronic hepatitis C;    liver fibrosis progression;    cirrhosis;   

DOI  :  

来源: DOAJ

【 摘 要 】

The major hepatological consequence of HCV infection is the progression to cirrhosis and its potential complications. Several factors have been clearly shown to be associated with fibrosis progression rate: duration of infection, age, male sex, consumption of alcohol, HIV coinfection and low CD4 count. As age and duration of infection increases, the risk of fibrosis increases and the impact of treatment (IFN) decreases. In conclusion, fibrosis progression has a progressive acceleration, sex, age and consumption of alcohol are strongly involved in this progression; the possibility to assess with nonagressive biochemical markers the fibrosis stage will probably allow in the future to identify other factors related to fibrosis progression.

【 授权许可】

Unknown