Influence of photobiomodulation and vitamin D on osteoblastic differentiation of human periodontal ligament stem cells and bone-like tissue formation through enzymatic activity and gene expression

Biomolecular Concepts

Abdelgwad Marwa¹  Abdelaziz Asmaa Mohamed²  Sabry Dina³  Abdelgawad Latifa Mohamed⁴ 

[1] Lecturer of Medical Biochemistry and Molecular Biology, Faculty of Medicine, Cairo University, Giza, Egypt;Master degree candidate in Medical Laser Applications Department, National Institute of Laser Enhanced Sciences (NILES), Cairo University, Giza, Egypt;Professor of Medical Biochemistry and Molecular Biology, Faculty of Medicine, Cairo University, Giza, Egypt;Professor of Medical Laser Applications, National Institute of Laser Enhanced Sciences (NILES), Cairo University, Giza, Egypt;

关键词: low-level laser;    dental stem cells;    runx2;    osteonectin;    growth curve;   

DOI  :  10.1515/bmc-2020-0016

来源: DOAJ

【 摘 要 】

Human periodontal ligament stem cells (HPDLSCs) are a unique population of mesenchymal stem cells (MSCs). Recently, the positive effects of photobiomodulation on the regulation of MSCs proliferation and osteogenic differentiation have gained significant attention. This study aimed to assess the effects of photobiomodulation and vitamin D (as an anabolic factor) on HPDLSCs for bone regeneration.

【 授权许可】

Unknown