Coagulation and Bleeding Management in Pediatric Extracorporeal Membrane Oxygenation: Clinical Scenarios and Review

Frontiers in Medicine

Lisa A. Hensch¹  Jun Teruya¹  Shiu-Ki Rocky Hui² 

[1] Coagulation, Texas Children's Hospital, Houston, TX, United States;Immunology, Baylor College of Medicine, Houston, TX, United States;;Department of Pathology &;Division of Transfusion Medicine &

关键词: anti-Xa assay;    acquired von Willebrand syndrome;    antifibrinolytic agents;    therapeutic plasma exchange;    antithrombin;    plasma hemoglobin;   

DOI  :  10.3389/fmed.2018.00361

来源: DOAJ

【 摘 要 】

Extracorporeal membrane oxygenation (ECMO) is a life-saving procedure that requires careful coagulation management. Indications for ECMO continue to expand, leading to more complicated patients treated by ECMO teams. At our pediatric institution, we utilize a Coagulation Team to guide anticoagulation, transfusion and hemostasis management in an effort to avoid the all-to-common complications of bleeding and thrombosis. This team formulates a coagulation plan in conjunction with a multidisciplinary ECMO team after careful review of all available laboratory data as well as the patient's clinical status. Here, we present our general strategies for ECMO management in various clinical scenarios and a review of the literature pertaining to coagulation management in the pediatric ECMO setting.

【 授权许可】

Unknown