The Framingham Heart Study: Populational CT-based phenotyping in the lungs and mediastinum

European Journal of Radiology Open

George R. Washko¹  Hiroto Hatabu²  Mark L. Schiebler³  Tetsuro Araki⁴  George T. O’Connor⁵ 

[1] Corresponding author at: Department of Radiology, Brigham and Women’s Hospital, Harvard Medical School, 75 Francis St., Boston MA, 02215, USA.;Department of Medicine, Boston University, Boston, MA, USA;Department of Pulmonology, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA;Department of Radiology, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA;Department of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA;

关键词: Framingham Heart Study;    CT;    Lung;    Thymus;    Interstitial lung abnormalities;    Pleural plaques;   

DOI  :  

来源: DOAJ

【 摘 要 】

The Framingham Heart Study (FHS) is one of the largest and established longitudinal populational cohorts. CT cohorts of the FHS since 2002 provided a unique opportunity to assess non-cardiac thoracic imaging findings. This review deals with image-based phenotyping studies from recent major publications regarding interstitial lung abnormalities (ILAs), pulmonary cysts, emphysema, pulmonary nodules, pleural plaques, normal spectrum of the thymus, and anterior mediastinal masses, concluding with the discussion of future directions of FHS CT cohorts studies in the era of radiomics and artificial intelligence.

【 授权许可】

Unknown