GATA2−/− human ESCs undergo attenuated endothelial to hematopoietic transition and thereafter granulocyte commitment

Cell Regeneration

Guangjin Pan¹  Juan Du¹  Pengfei Wu¹  Xi Shi¹  Peng Li¹  Yi Zheng¹  Jinyong Wang¹  Qianyu Chen¹  Ning Ma¹  Jinglei Cai¹  Ke Huang¹  Minghui Meng¹  Wei Li¹  Duanqing Pei¹  Zhongzhou Yang¹  Shubin Chen¹  Jian Zhang¹  Xin Chen¹  Wenqian Wang²  Jiajun Liu²  Xiaoya Dong²  Xiaofang Sun³  Yuhang Li⁴ 

[1] CAS Key Laboratory of Regenerative Biology, South China Institute for Stem Cell Biology and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou 510530, China;Department of Hematology, Sun Yat-sen University, Guangzhou 510630, China;Key Laboratory for Major Obstetric Diseases of Guangdong Province, Guangzhou, China;South China University of Technology, Guangzhou 510641, China;

关键词: hESCs;    GATA2;    EHT;    HPC;    Granulocyte;    Notch signaling;   

DOI  :  10.1186/s13619-015-0018-7

来源: DOAJ

【 授权许可】

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