SARS-CoV-2: vaccines in the pandemic era

Military Medical Research

Dan-Dan Li¹  Qi-Han Li¹ 

[1] Institute of Medical Biology, Chinese Academy of Medicine Science & Peking Union Medical College, Yunnan Key Laboratory of Vaccine Research and Development on Severe Infectious Diseases;

关键词: SARS-CoV-2;    COVID-19;    Vaccine;    Vaccine candidate;    Clinical trials;   

DOI  :  10.1186/s40779-020-00296-y

来源: DOAJ

【 摘 要 】

Abstract Coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has caused millions of infections and deaths worldwide since its emergence in December 2019. As there is little or no natural immunity in the human population or specific anti-COVID-19 drugs, researchers from the government, academia and industry are developing vaccines at an unprecedented speed to halt the pandemic. In this review, the results of animal experiments and clinical trials on several vaccine technical platforms are summarized, and several challenges are also discussed to further promote the development, evaluation and application of vaccines during the challenging situation of the global pandemic.

【 授权许可】

Unknown