Overweight modifies the association between long-term ambient air pollution and prehypertension in Chinese adults: the 33 Communities Chinese Health Study

Environmental Health

Michael G. Vaughn¹  Min Nian¹  Guang-Hui Dong²  Zhengmin Min Qian²  Yan-Peng Tian²  Steven W. Howard³  Duo-Hong Chen³  Huimin Ma⁴  Xiao-Wen Zeng⁵  Bo-Yi Yang⁶  Xiang Xiao⁶  Chuan Zhang⁶  John Phillip Pemberton⁷  Li-Wen Hu⁸ 

[1] Department of Preventive Medicine, School of Public Health, Sun Yat-sen University;Guangdong Provincial Engineering Technology Research Center of Environmental and Health risk Assessment;Department of Epidemiology, College for Public Health and Social Justice, Saint Louis University;Department of Health Management & Policy, College for Public Health & Social Justice, Saint Louis University;Guangdong Environmental Monitoring Center, State Environmental Protection Key Laboratory of Regional Air Quality Monitoring, Guangdong Environmental Protection Key Laboratory of Atmospheric Secondary Pollution;Guangzhou Key Laboratory of Environmental Pollution and Health Risk Assessment;School of Social Work, College for Public Health and Social Justice, Saint Louis University;State Key Laboratory of Organic Geochemistry and Guangdong Key Laboratory of Environmental Protection and Resources Utilization, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences;

关键词: Ambient air pollution;    Chinese;    Interaction;    Overweight;    Prehypertension;   

DOI  :  10.1186/s12940-018-0401-2

来源: DOAJ

【 摘 要 】

Abstract Background Research regarding the interaction of ambient air pollution and overweight on prehypertension is scarce. We aimed to test whether overweight modifies the association between long-term exposure to ambient air pollution and prehypertension in Chinese adults. Methods A total of 16,188 Chinese adults, aged 18–74 years old, from 33 communities in 3 Northeastern Chinese cities were evaluated. Three-year average levels of particles with an aerodynamic diameter ≤ 10 μm (PM10), sulfur dioxides (SO2), nitrogen dioxides (NO2), and ozone (O3) were calculated at monitoring stations. Generalized additive models and 2-level regression analyses were applied. Results We observed significant interactions between air pollutants and overweight on prehypertension and blood pressure. The associations of PM10, SO2, NO2, and O3 with prehypertension were significant among overweight participants (Prevalence Rate Ratios (PRRs) per interquartile range (IQR) of air pollutants: 1.14–1.20), but not among normal weight participants (PRRs: 0.98–1.04). PM10, SO2, and O3 were significantly associated with systolic blood pressure (SBP), and the magnitudes of these associations were higher among overweight adults (increases in SBP per IQR of air pollutants: 1.82–4.53 mmHg) than those among normal weight adults (increases in SBP: 0.42–0.61 mmHg). For diastolic blood pressure (DBP), significant associations were mainly observed in overweight participants (increases in DBP: 0.80–1.63 mmHg). Further stratified analyses showed that all these interactions were stronger in women, the older, and participants living in areas with lower income levels or higher population density. Conclusions Being overweight may enhance the effects of ambient air pollution on prehypertension and blood pressure in Chinese adults.

【 授权许可】

Unknown