Treatment and prophylaxis of moderate and severe bronchopulmonary dysplasia in premature neonates

Medičnì Perspektivi

A.V. Bolonska¹  O.Yu.Sorokina² 

[1] Dnipro State Medical University, V. Vernadsky str., 9, Dnipro, 49044, Ukraine;Dnipro State Medical University, V. Vernadsky str., 9, Dnipro, 49044;

关键词: bronchopulmonary dysplasia;    premature;    neonates;    newborns;    respiratory support;    prophylaxis;   

DOI  :  10.26641/2307-0404.2021.3.241961

来源: DOAJ

【 摘 要 】

Bronchopulmonary dysplasia in premature neonates leads to physical and mental developmental disorders and behavioral problems and associated with frequent rehospitalizations and long hospital stay. Study objective: to study the predictors of bronchopulmonary dysplasia development in premature neonates in structure of intensive care. Study design: A retrospective cohort analysis was performed in 127 children recruited from two NICU of Dnipro between January 2016 to March 2020. Inclusion criteria: preterm neonates 28-32 gestation weeks with respiratory distress syndrome (RDS). Results demonstrated that every day of mechanical ventilation, supplemental oxygen with FiO2 more than 30% and cardiac drugs usage increased risk of bronchopulmonary dysplasia development by 15-20%. In conclusion, finding out predictors of bronchopulmonary dysplasia helps to improve  and prudently use usual treatment regimens in premature neonates and decrease the frequency of moderate and severe bronchopulmonary dysplasia.

【 授权许可】

Unknown