Cells | |
Astrocytic Regulation of Neural Circuits Underlying Behaviors | |
Hyosang Lee1  Sun-Nyoung Hwang1  Kain Seo2  Jae Seung Lee2  | |
[1] Convergence Research Advanced Centre for Olfaction, Daegu Gyeongbuk Institute of Science and Technology (DGIST), Daegu 42988, Korea;Department of Brain and Cognitive Sciences, DGIST, Daegu 42988, Korea; | |
关键词: astrocyte; neural circuit; behavior; GFAP; chemogenetics; optogenetics; | |
DOI : 10.3390/cells10020296 | |
来源: DOAJ |
【 摘 要 】
Astrocytes, characterized by a satellite-like morphology, are the most abundant type of glia in the central nervous system. Their main functions have been thought to be limited to providing homeostatic support for neurons, but recent studies have revealed that astrocytes actually actively interact with local neural circuits and play a crucial role in information processing and generating physiological and behavioral responses. Here, we review the emerging roles of astrocytes in many brain regions, particularly by focusing on intracellular changes in astrocytes and their interactions with neurons at the molecular and neural circuit levels.
【 授权许可】
Unknown