The First Bacterial Endocarditis Due to Achromobacter xylosoxidans in a Dog

Pathogens

Nicole Luckschander-Zeller¹  Alejandra Carranza Valencia¹  Frank Künzel¹  Verena Steiner¹  Mato Markovic¹  Franz Allerberger²  Werner Ruppitsch²  Adriana Cabal Rosel²  Joachim Spergser³  Igor Loncaric³  Michael P. Szostak³ 

[1] Department for Companion Animals and Horses, Clinical Unit of Internal Medic and Small Animals, University of Veterinary Medicine, 1210 Vienna, Austria;Institute of Medical Microbiology and Hygiene, Austrian Agency for Health and Food Safety, 1090 Vienna, Austria;Institute of Microbiology, University of Veterinary Medicine, 1210 Vienna, Austria;

关键词: newly emerging bacteria;    bacteremia;    reserve antibiotic;    endocarditis;    canine;   

DOI  :  10.3390/pathogens10121580

来源: DOAJ

【 摘 要 】

Infectious endocarditis (IE) in dogs is often associated with a high mortality rate as diagnostic work-up as well as antibiotic treatment might be challenging. The present case describes bacteremia in a dog caused by Achromobacter xylosoxidans, leading to an infectious endocarditis. Achromobacter xylosoxidans (A. xylosoxidans) is an aerobic Gram-negative rod-shaped bacterium, which has been associated with multiple nosocomial opportunistic diseases in human medicine. One such manifestation of A. xylosoxidans infection is endocarditis. A. xylosoxidans infections are challenging to treat due to the reduced effectiveness of a wide range of antimicrobial agents. To date, only a few case reports of infections with A. xylosoxidans in animals have been described. This is the first case report of A. xylosoxidans endocarditis in a dog. Whole-genome sequencing was performed to determine the sequencing type and to gain more information about this bacterium regarding its intrinsic resistance genes. With this case report, we seek to increase awareness of A. xylosoxidans as an opportunistic nosocomial pathogen in dogs and to provide a short summary regarding the current state of general knowledge and known resistance patterns.

【 授权许可】

Unknown