Phospho sulfonic acid: A novel and efficient solid acid catalyst for the one-pot preparation of 2H-indazolo[2,1-b]-phthalazine-triones

Journal of the Serbian Chemical Society

关键词: indazolo[2,1-b]phthalazine-trione;    multicomponent reaction;    phthalhydrazide;    dimedone;    solvent-free;    phospho sulfonic acid;   

DOI  :  10.2298/JSC120508088K

来源: DOAJ

【 摘 要 】

The efficient one-pot condensation of aldehyde, dimedone, and phthalhydrazidehas been achieved in the presence of a catalytic amount of phospho sulfonicacid as a novel environmentally benign heterogeneous solid acid undersolvent-free conditions. A diversified 2H-indazolo[1,2-b]phthalazinetrionederivatives were prepared in good to excellent yields in short time. Theeconomical factors (time, cost, waste etc.) for this three-component reactionhold promise for the future of organic synthesis.

【 授权许可】

Unknown