A Comparison of Lung Ultrasound and Computed Tomography in the Diagnosis of Patients with COVID-19: A Systematic Review and Meta-Analysis

Diagnostics

Qi Wang¹  Meng Lv²  Hyeong Sik Ahn³  Xiaojuan Xiao⁴  Junqiang Lei⁵  Ling Wang⁶  Ying Zhu⁷  Mengshu Wang⁷  Jinhui Tian⁷  Yang Song⁸  Janne Estill⁹  Myeong Soo Lee^1,10  Xufei Luo^1,11 

[1] Department of Health Research Methods, Evidence and Impact, Faculty of Health Sciences, McMaster University, Hamilton, ON L8S 4L8, Canada;Department of Nephrology, Children’s Hospital of Chongqing Medical University, Chongqing 400014, China;Department of Preventive Medicine, Korea University, Seoul 02841, Korea;Department of Radiology, The Eighth Affiliated Hospital, Sun Yat-sen University, Shenzhen 518033, China;Department of Radiology, The First Hospital of Lanzhou University, Lanzhou 730000, China;Department of Ultrasound, People’s Hospital of Gansu Province, Lanzhou 730000, China;Evidence-Based Medicine Centre, School of Basic Medical Sciences, Lanzhou University, Lanzhou 730000, China;Iberoamerican Cochrane Centre-Biomedical Research Institute Sant Pau (IIB Sant Pau), 08025 Barcelona, Spain;Institute of Global Health, University of Geneva, 1211 Geneva, Switzerland;Korea Institute of Oriental Medicine, Daejeon 34054, Korea;School of Public Health, Lanzhou University, Lanzhou 730000, China;

关键词: COVID-19;    systematic review;    POCUS;    lung ultrasound;    computed tomography;   

DOI  :  10.3390/diagnostics11081351

来源: DOAJ

【 摘 要 】

Background Lung ultrasound (LUS) and computed tomography (CT) can both be used for diagnosis of interstitial pneumonia caused by coronavirus disease 2019 (COVID-19), but the agreement between LUS and CT is unknown. Purpose to compare the agreement of LUS and CT in the diagnosis of interstitial pneumonia caused by COVID-19. Materials and Methods We searched PubMed, Cochrane library, Embase, Chinese Biomedicine Literature, and WHO COVID-19 databases to identify studies that compared LUS with CT in the diagnosis of interstitial pneumonia caused by COVID-19. We calculated the pooled overall, positive and negative percent agreements, diagnostic odds ratio (DOR) and the area under the standard receiver operating curve (SROC) for LUS in the diagnosis of COVID-19 compared with CT. Results We identified 1896 records, of which nine studies involving 531 patients were finally included. The pooled overall, positive and negative percentage agreements of LUS for the diagnosis of interstitial pneumonia caused by COVID-19 compared with CT were 81% (95% confidence interval [CI] 43–99%), 96% (95% CI, 80–99%, I² = 92.15%) and 80% (95%CI, 60–92%, I² = 92.85%), respectively. DOR was 37.41 (95% CI, 9.43–148.49, I² = 63.9%), and the area under the SROC curve was 0.94 (95% CI, 0.92–0.96). The quality of evidence for both specificity and sensitivity was low because of heterogeneity and risk of bias. Conclusion The level of diagnostic agreement between LUS and CT in the diagnosis of interstitial pneumonia caused by COVID-19 is high. LUS can be therefore considered as an equally accurate alternative for CT in situations where molecular tests are not available.

【 授权许可】

Unknown