Novel Chitosan Derivatives and Their Multifaceted Biological Applications

Applied Sciences

Iyyakkannu Sivanesan¹  Nazim Hasan²  Syed Kashif Ali²  Juhyun Shin³  Jae-Wook Oh³  Judy Gopal⁴  Manikandan Muthu⁴ 

[1] Department of Bioresources and Food Science, Institute of Natural Science and Agriculture, Konkuk University, 1 Hwayang-dong, Gwangjin-gu, Seoul 05029, Korea;Department of Chemistry, Faculty of Science, Jazan University, Jazan P.O. Box 114, Saudi Arabia;Department of Stem Cell and Regenerative Biotechnology, Konkuk University, Seoul 143-701, Korea;Laboratory of Neo Natural Farming, Chunnampet 603 401, Tamil Nadu, India;

关键词: chitosan derivatives;    antimicrobial;    antioxidant;    anticancer;    biomedical applications;   

DOI  :  10.3390/app12073267

来源: DOAJ

【 摘 要 】

Chitosan is a rather attractive material, especially because of its bio-origins as well as generation from exoskeletal waste. As the mantle has been effectively transferred from chitin to chitosan, so has it been extrapolated to in-house synthesized novel chitosan derivatives. This review comprehensively lists the available novel chitosan derivatives (ChDs) and summarizes their biological applications. The fact that chitosan derivatives do comprise multifaceted biological applications is attested by the voluminous reports on their varied contributions. However, this review points out to the fact that there has been selective focus on bio functions such as antifungal, antioxidant, antibacterial, whereas other biomedical applications and antiviral applications remain relatively less explored. With their current functionality record, there is definitely no doubt that the plethora of synthesized ChDs will have a profound impact on the unexplored biological aspects. This review points out this lacuna as room for future exploration.

【 授权许可】

Unknown